Peter L. Davies, Ph.D., FRSC

Canada Research Chair in Protein Engineering

Professor, School of Medicine

Dept of Biological and Molecular Sciences

 

Office:

Botterell Hall, Room 643

Queen's University

Kingston, Ontario

Canada K7L 3N6

e-mail: peter.davies@queensu.ca

Office:  613-533-2983

Fax:     613-533-2497

webpage: peterldavies.com

Meet our team

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Dr. Peter L. Davies

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We are studying the relationship between structure and function in three different types of proteins: 1) antifreeze proteins (AFPs), which help organisms resist or tolerate freezing; 2) bacterial adhesins, which help their bacterial hosts bind and colonize specific surfaces; and 3) calpains, enzymes that selectively cut proteins within the cell in response to calcium signaling.

Included in our research on antifreeze proteins is the study of bacterial ice nucleation proteins, which cause frost damage to plants. Although they have the opposite function to antifreeze proteins – starting ice growth, rather than stopping it – there is evidence to suggest they both use a similar mechanism of action in organizing ice-like waters on the protein surface.

Our research projects involve bioinformatics, gene synthesis and cloning, the production and purification of natural and recombinant proteins, biophysical and structural analyses, cellular analyses, protein modeling and protein engineering.

We are grateful to the Canadian Institutes of Health Research (CIHR), the Natural Sciences and Engineering Research Council (NSERC) and the Muscular Dystrophy Association (MDA) for funding our research.

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Queen's University

Kingston Ontario Canada

© 2018  Peter L. Davies

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